Thanks TPT for the reply.

And why not critique the title and abstract? It is equally important as the conclusion. Almost everyone first reads the title, then the abstract and then if it is interesting/what you are looking for, read the full text. This is the order even when you do a systematic review.  Any any critical evaluation of a study usually includes the abstract and title.

I know Brian of evidence based fitness came with a post talking about he same criticisms. But I don’t think it should have been the major argument in his post.

And I do think wherever they tried to extrapolate the language used was pretty cautionary. And the reference they quotes(52) indeed shows substantial hypertrophy with 30% MVC in humans. And the other two studies hows how they found protein synthesis to be greater AND went on to do long term studies measuring strength and muscle and found it be true. So there is a good reason to study protein synthesis or acute variables. Show the results with an acute study and then get a grant to study with more people and longer duration.

What do you think are the designs and other issues?

Hi Mavros,

What determines absolute strength. We can break it down into two: Muscle Mass and neural factors.

Now explain what you said with these two variables.

anoopbal - 17 November 2010 01:36 PM

Thanks TPT for the reply.

And why not critique the title and abstract? It is equally important as the conclusion. Almost everyone first reads the title, then the abstract and then if it is interesting/what you are looking for, read the full text. This is the order even when you do a systematic review.  Any any critical evaluation of a study usually includes the abstract and title.

I know Brian of evidence based fitness came with a post talking about he same criticisms. But I don’t think it should have been the major argument in his post.

And I do think wherever they tried to extrapolate the language used was pretty cautionary. And the reference they quotes(52) indeed shows substantial hypertrophy with 30% MVC in humans. And the other two studies hows how they found protein synthesis to be greater AND went on to do long term studies measuring strength and muscle and found it be true. So there is a good reason to study protein synthesis or acute variables. Show the results with an acute study and then get a grant to study with more people and longer duration.

What do you think are the designs and other issues?

Link to this, please.

http://evidencebasedfitness.blogspot.com/2010/08/if-youre-going-to-claim-to-improve.html

anoopbal - 12 November 2010 04:30 AM

Welcome to the Exercise Biology forum, TPT! I think we had some discussions in the forum about the study.

Phillip is doing a long term study which measures strength and muscle growth and we would know something then. I will do a review of this study soon.

Any word on the long term study?

Not yet. Might see in a few months

Hi Anoop - Any news on the Phillip’s study?

Not yet, Omar.

Why don’t you try it out for weeks for legs and see? Pick leg extension or leg curls. After weeks, alternate with heavier weights. Alternate the program 2 times.There will be obviously a placebo effect, but cannot help it.

There is no risk here unless you are a competing bodybuilder. This it eh n=1 trial.

from a recent review by Phillip:

As further evidence of the efficacy of low-load,
high volume resistance exercise and that acute
muscle protein synthetic responses are predictive
of long-term adaptation, we recently found that
10 weeks of knee extension resistance exercise
(3 sets, 4 times per week) at 30 and 80% of 1RM
to failure, induced equivalent gains in quadriceps
lean mass and strength in healthy young men
(Mitchell and Phillips et al. unpublished observations).

So I think they showed comparable gains which is impressive!

the subjects were untrained?

I m guessing beginners. In the acute study, the subjects were” Participants reported engaging in lower body
exercise such as resistance exercise alone or in combination with cycling more than 3 times weekly for the prior 6 months”.

It is still really interesting when all the evidence showed that 30Rm is too light to work compared to a 10RM. It shows that Type 2 fiber recruitment might be the key here.

And we don’t know about trained. All these 20 rep squat stories shows that high rep culd be effective. How effective? Nobody knows.