Why is it Hard to Maintain Your Lost Weight?
November 27 2011
We know that 80% of the obese & overweight people who lose weight, gain most of it back within a few years. Is it because they lack the discipline or is there physiological mechanisms beyond their control that is driving the weight back.
It is now clear your body weight is regulated by your brain. There are numerous hormones in your body that controls your appetite to keep your body weight within a certain range.
Leptin: Leptin - one of the most important hormones- is primarily produced from fat cells and its circulating level is directly proportional to body fat levels.
Ghrelin: Ghrelin is released from the stomach and its primary purpose is it stimulates hunger,
Cholecystokinin(CKK): CKK is another intestinal hormon which suppresses appetite.
Eating less causes profound reductions in energy expenditure,leptin, cholecystokinin and increase in ghrelin and appetite all of which promote weight regain.
What was the study purpose?
The purpose of the study was to see whether these fluctuations in these appetite regulating hormones persists with prolonged maintenance of reduced weight.If it persists, it maybe be one of the reasons why people gain back weight so easily.
What was the sudy design?
The study involved 50 overweight or obese participants in a 10 week weight loss program. They measured different hormones and appetite levels before the weight loss, after the weight loss (10 weeks), and after 62 weeks of weight maintenance.
What were the results?
The mean weight loss was around 26 lbs after 10 weeks. There were significant changes in hormones and appetite after weight loss, and all these changes persisted even after 62 weeks.
The raph shows how hunger and 'desire to eat' were significantly higher after 10 weeks and 62 weeks compared to baseline. In short, it just means that your body is trying to get back to the baseline weight.
Conclusions
There are multiple compensatory mechanisms vigorously resisting weight loss in obese and overweight people.You didn't gain the weight back just because 'life got busy' or you lacked the will power.
